Dear authors,

both reviewers acknowledge the improvements that you have made to the revised manuscript. They still raise, however, the issue of presentation quality and readability of the manuscript (which is outside the regular copy-editing services) to ensure that its main messages are delivered in an optimal way. Reviewer #2 also gives useful tips on how this can be better achieved.

I could also recommend asking for a colleague outside your direct field, but who could represent the readership of ACP, to read through the manuscript and help make the description of the methods and the key points as clear as possible.

I will be happy to reconsider your manuscript for potential publication in ACP after one more round of revision, focusing on presentation of the results and readability of the manuscript.